- POCD
- Dementia
- Series of organic brain syndromes associated with irreversible pathology
- Delirium
- Acute onset of disturbed mental function
- Predisposing factors
- Increasing age
- GA > RA
- Long duration
- Respiratory complications
- Low IQ
- Re-operation
- Post-op infection
- Neuro procedures
- CEA/CPB
- Anaesthetic options
- Premedication
- Avoid benzodiazapines
- Regional better for early POCD (but not for late POCD)
- Anaesthetic assessment
- MMSE
- Consider regional technique
- Causes
- Emboli
- Physiological disturbances
- Pre-existing cognitive dysfunction
- Others
- Serum neuron endolase
- S100 β-protein
- CEACCP
Link:ceaccp.oxfordjournals.org/content/6/1/37.full.pdf