- Gastrectomy
- MRC Gastric Infusional Chemotherapy (MAGIC) trial shows peri-operative CXT (epirubicin, cisplatin & flurouracil) confers benefit
Link:www.nejm.org/doi/pdf/10.1056/NEJMoa055531
- Commonly causes cardiotoxicity & thrombocytopenia
- May require resection of the spleen or distal pancreas
- Pre-op
- May have had staging laparoscopy
- May be smokers with IHD, HT, resp disease, reflux or poor nutritional status
- May have had pre-op CXT
- Bloods
- FBC, U&E, LFT
- Echo, PFTs, CXR, ECG
- Intra-op
- RSI
- Epidural
- Invasive Monitoring
- Complications
- CV/resp complications
- TED
- Surgical complications
- Weight loss
- Dumping syndrome
- Bloating/steatorhoea
- Anaemia
- B12 supplementation required
- CEACCP
Link:ceaccp.oxfordjournals.org/content/9/2/65.full.pdf