- Complications of blood transfusion
Link:www.shotuk.org/home
- Risks Of Blood Transfusion
- Immunological
- Immediate Haemolytic: due to ABO incompatibility
Delayed haemolytic: due to red cell antibody due to previous transfusion
Febrile non-haemolytic reaction: due to recipient anti-leucocyte antibodies
Anaphylaxis
Urticaria
TRALI: due to anti leucocyte antibodies in donor blood
- Infectious
- Hep B, C, HIV, Malaria, CMV, Brucellosis, bacterial contamination, prions
- Physiological
- Hyperkalaemia
Hypocalcaemia
Acidosis
Dilution coagulopathy
Thrombocytopenia
Hypothermia
Impaired oxygen delivery
DIC
TACO
Immunomodulation
- Late
- Infection transmission
- Viral (hep A/B/C, HIV, CMV)
- Bacterial (salmonella, treponeum pallidum)
- Parasites (malaria, toxoplasmosis)
- Graft vs host
- Iron overload
- Immune sensitisation
- Early
- Haemolytic reactions
- Non-haemolytic febrile reactions
- Allergic reaction to proteins eg IgA
- TRALI
- Reactions due to bacterial contamination
- TACO
- Air embolus
- Thrombophlebitis
- Hyperkalaemia
- Citrate toxicity
- Hypothermia
- Clotting abnormalities
- CEACCP
Link:ceaccp.oxfordjournals.org/content/6/6/225.full.pdf