- Autologous blood transfusion
- Allogenic Tx risks transmission of hep viruses, HIV, HTLV vCJD (reduced by leukodepletion)
- Techniques
- Cell salvage
- Via intra-op cell salvage (ICS) or post-op cell salvage (PoCS).
- Pre-operative autologous donation (PAD)
- Acute normovolaemic haemodilution (ANH)
- Advantages
- Reduced risk of transmission of infection
- Reduced transfusion reactions
- May be acceptable to some JW patients
- Safer transfusion in patients with rare blood groups/antibodies
- Reduces demand on allogenic supplies
- Disadvantages
- Cost pressure
- Logistics for collection/storage
- Unused blood is wasted and can't be returned to donor pool
- Increased risk of bacterial contamination.
- Pre-op autologous blood transfusion
- 1 unit taken every few days prior to elective surgery, up to 4 units
- Last donation 48-72hrs before surgery
- Useful in patients with rare blood groups/multiple transfusions
- CI with bowel surgery, malignant disease & questioned in obstetrics
- Complications of ICS
- Electrolyte disturbances (low Mg, Ca, albumin)
- Dilutional coagulopathy
- DIC (salvaged blood syndrome)
- Air embolus
- CEACCP
Link:ceaccp.oxfordjournals.org/content/6/5/192.full.pdf