• Awareness
    Link:www.nationalauditprojects.org.uk/NAP5_home
    • Explicit awareness (1:3000 GAs - recall without pain is more common)
      • Recall spontaneous or provoked by post-op questioning or events
      • Commoner in cardiac and emergency procedures
    • Implicit awareness
      • Not consciously recalled but affects performance at a later date
    • Twice as common if NMBDS used
      Frequently due to poor anaesthetic technique
    • Consequences
      • Insomnia, depression, anxiety, PTSD, flashbacks, fear of future GA
    • Depth of anaesthesia monitoring
      Link:EEG for depth of anaesthesia
      • Clinical
      • EtCO₂
      • BIS
      • Auditory evoked potentials
      • Entropy
      • Isolated forearm technique
      • Lower oesophageal sphincter tone
      • Forehead galvanometry
    • Signs of awareness may be masked by diseases or medication
    • Clinical examination remains important
      • Tachycardia
      • Hypertension
      • Sweating
      • Tear production
      • Movement
      • Tachypnoea
      • Pupillary dilatation
    • Equipment malfunction
      • Breathing systems and vaporiser malfunction. IV cannula disconnection or pump failure
    • Resistance to anaesthetic agents
      • Pyrexia, hyperthyroidism, obesity, alcohol, drugs, smokers, young age.
    • Selection of inadequate anaesthetic dose
      • Associated with emergency surgery, cardiac surgery and C-section
      • May be higher variability for 'MAC' values with IV agents. A MAC of >0.8 is unlikely to result in awareness. MAC >1 eliminates spontaneous recall
    • CEACCP
      Link:ceaccp.oxfordjournals.org/content/5/6/183.full.pdf